Investigating biological processes often requires model systems that mimic naturally occurring physiological environments. Many animal models and cell lines have served as gold standard tools for biomedical researchers to investigate biological functions in laboratories. Yet, many vital bio-activities such as hormones production rely on fluid dynamics to propagate signalling molecules at the right place and time throughout the body. In investigating such long-range communication mechanisms, a need exist to precisely mimic and control physiological fluid environments in laboratory settings. The present design serves as a first iteration concept of a microfluidic pumping system to mimic physiological fluid dynamics.